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Alternativ splicing: en process som medför att flera olika mRNA-transkript bildas från individuella gener / Alternative splicing: a process that leads to the formation of several different mRNA-transcripts from individual genes

<p>This review article presents the splicing process during messenger RNA maturation and how it is regulated by different <em>Cis</em>-regulatory RNA-sequence elements and splicing factors. A more detailed description of the process alternative splicing and its importance to the function of genes from the model organism <em>Arabidopsis thaliana</em> is also given. A single eukaryotic gene can by the process alternative splicing (AS) give rise to a number of functionally mature mRNA-molecules, which in turn encodes for structurally and/or functionally different proteins. During the course of evolution, the process alternative splicing has thus shown to be effective in increasing transcriptome and proteome diversity of most eukaryotic organisms. This suggests therefore that the dominant theory in molecular biology, a gene encodes for a protein, needs to be corrected. A future challenge is to determine the function of the proteins obtained from a given gene by alternative splicing.</p>

Identiferoai:union.ndltd.org:UPSALLA/oai:DiVA.org:liu-56880
Date January 2010
CreatorsSavas, Isabella
PublisherLinköping University, Department of Physics, Chemistry and Biology
Source SetsDiVA Archive at Upsalla University
LanguageSwedish
Detected LanguageEnglish
TypeStudent thesis, text
RelationLITH-IFM-G-Ex--10/2338--Ex

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