by So Mei Po. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2000. / Includes bibliographical references (leaves 105-111). / Abstracts in English and Chinese. / Title Page --- p.i / Table of Contents --- p.ii / List of Tables --- p.v / List of Figures --- p.vii / Abbreviations --- p.xi / Acknowledgements --- p.xii / Abstract --- p.xiii / Chapter CHAPTER ONE --- INTRODUCTION / Chapter 1.1 --- Chiral Recognition Detected by Mass Spectrometry --- p.1 / Chapter 1.2 --- Fast Atom Bombardment Mass Spectrometry --- p.7 / Chapter 1.2.1 --- Desorption/Ionization in FAB --- p.7 / Chapter 1.2.1.1 --- Matrix --- p.8 / Chapter 1.2.1.2 --- Atom/Ion Guns --- p.9 / Chapter 1.3 --- Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry --- p.9 / Chapter 1.3.1 --- Development of Matrix-Assisted Laser Desorption/Ionization --- p.10 / Chapter 1.3.2 --- Matrix-Assisted Laser Desorption/Ionization --- p.11 / Chapter 1.3.2.1 --- The Matrix --- p.12 / Chapter 1.3.2.2 --- Mechanisms of Ion Formation --- p.12 / Chapter 1.3.2.2.1 --- Desorption --- p.13 / Chapter 1.3.2.2.2 --- Ionization --- p.13 / Chapter 1.4 --- Blackbody Infrared Radiative Dissociation (BIRD) --- p.14 / Chapter 1.4.1 --- Photodissociation --- p.15 / Chapter 1.4.2 --- Blackbody Infrared Radiative Dissociation --- p.15 / Chapter 1.5 --- Outline of the Present Work --- p.18 / Chapter CHAPTER TWO --- INSTRUMENTATION AND EXPERIMENTAL / Chapter 2.1 --- Time-of-flight Mass Spectrometry --- p.19 / Chapter 2.1.1 --- Delayed Extraction --- p.23 / Chapter 2.1.2 --- Instrumentation --- p.24 / Chapter 2.1.2.1 --- Laser System --- p.24 / Chapter 2.1.2.2 --- Ion Source --- p.26 / Chapter 2.1.2.3 --- Reflector --- p.27 / Chapter 2.1.2.4 --- Detector --- p.27 / Chapter 2.1.2.5 --- Data Acquisition and Computer Control --- p.27 / Chapter 2.2 --- Fourier Transform Ion cyclotron Resonance Mass Spectrometry --- p.28 / Chapter 2.2.1 --- Ion Source --- p.29 / Chapter 2.2.1.1 --- Fast Atom Bombardment Mass spectrometry (FABMS) --- p.29 / Chapter 2.2.2 --- Electrostatic Ion Focusing System --- p.31 / Chapter 2.2.3 --- ICR Analyzer Cell and Magnet --- p.34 / Chapter 2.2.4 --- Data Acquisition and Handling system --- p.38 / Chapter 2.3 --- Experimental --- p.38 / Chapter 2.3.1 --- Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry --- p.38 / Chapter 2.3.1.1 --- Sample Preparation --- p.38 / Chapter 2.3.1.2 --- Mass Spectrometric Analysis --- p.39 / Chapter 2.3.2 --- Fast Atom Bombardment Mass Spectrometry --- p.39 / Chapter 2.3.2.1 --- Sample preparation --- p.39 / Chapter 2.3.2.2 --- Blackbody Infrared Radiative Dissociation --- p.39 / Chapter CHAPTER THREE --- HOST-GUEST COMPLEXES DETECTED BY MATRIX- ASSISTED LASER DESORPTION/IONIZATION MASS SPECTROMETRY / Chapter 3.1 --- Introduction --- p.42 / Chapter 3.2 --- Sample Preparation --- p.45 / Chapter 3.3 --- Results and Discussions --- p.49 / Chapter 3.3.1 --- Cyclodextrins - Cyclic Maltooligosaccharides --- p.49 / Chapter 3.3.2 --- Maltooligosaccharide --- p.55 / Chapter 3.4 --- Conclusions --- p.64 / Chapter CHAPTER FOUR --- DIFFERENTIATION OF ENANTIOMERS USING MALDI-TOF-MS / Chapter 4.1 --- Introduction --- p.65 / Chapter 4.2 --- Experimental --- p.67 / Chapter 4.2.1 --- MALDI-MS Studies --- p.67 / Chapter 4.2.2 --- Calculation --- p.68 / Chapter 4.3 --- Results and Discussions --- p.69 / Chapter 4.3.1 --- MALDI-MS Studies --- p.69 / Chapter 4.3.2 --- Calculations --- p.74 / Chapter 4.4 --- Conclusion --- p.81 / Chapter CHAPTER FIVE --- BLACKBODY INFRARED RADIATION DISSOCIATION (BIRD) OF DIASTEREOCOMPLEXES / Chapter 5.1 --- Introduction --- p.86 / Chapter 5.2 --- Experimental --- p.88 / Chapter 5.3 --- Result and Discussion --- p.89 / Chapter 5.3.1 --- BIRD of Amino-acid/Cyclodextrin complexes --- p.89 / Chapter 5.3.2 --- BIRD of Proton-bound Amino Acid Dimers and Amino Acid/dipeptide Dimers --- p.91 / Chapter 5.4 --- Conclusion --- p.102 / Chapter CHAPTER SIX --- CONCLUSIONS AND FURTHER WORKS / Chapter 6.1 --- Conclusions --- p.103 / Chapter 6.2 --- Further Works --- p.104 / REFERENCES --- p.105
| Identifer | oai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_323139 |
| Date | January 2000 |
| Contributors | So, Mei Po., Chinese University of Hong Kong Graduate School. Division of Chemistry. |
| Source Sets | The Chinese University of Hong Kong |
| Language | English, Chinese |
| Detected Language | English |
| Type | Text, bibliography |
| Format | print, xix, 111 leaves : ill. ; 30 cm. |
| Rights | Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
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