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SMARTPHONE BASED SICKLE CELL DISEASE DETECTION AND ITS TREATMENT MONITORING FOR POINT-OF-CARE SETTINGS

The majority of Sickle Cell Disease (SCD) prevalence is found in Sub-Saharan Africa, where 80% of the world’s population who suffer from this disease are born. Due to a lack of diagnosis and early treatments, 50-90% of these children will die before they reach the age of five. Current methods used for diagnosing SCD are based on hemoglobin analysis such as capillary electrophoresis, ion-exchange high-performance liquid chromatography, and isoelectric focusing. They require expensive laboratory equipment and are not feasible in these low-resource countries. It is, therefore, imperative to develop an alternative and cost-effective method for diagnosing and monitoring of SCD. This thesis aims to address the development and evaluation of a smartphone-based optical setup for the detection of SCD. This innovative technique can potentially be applied for low cost and accurate diagnosis of SCD and improve disease management in resource-limited settings where the disease exhibits a high prevalence. This Point-of-Care (POC) based device offers the potential to improve SCD diagnosis and patient care by providing a portable and cost effective device that requires minimal training to operate and analyze. / Includes bibliography. / Thesis (M.S.)--Florida Atlantic University, 2020. / FAU Electronic Theses and Dissertations Collection

Identiferoai:union.ndltd.org:fau.edu/oai:fau.digital.flvc.org:fau_42620
ContributorsIlyas, Shazia (author), Asghar, Waseem (Thesis advisor), Florida Atlantic University (Degree grantor), Department of Computer and Electrical Engineering and Computer Science, College of Engineering and Computer Science
PublisherFlorida Atlantic University
Source SetsFlorida Atlantic University
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation, Text
Format73 p., application/pdf
RightsCopyright © is held by the author with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder., http://rightsstatements.org/vocab/InC/1.0/

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