Indiana University-Purdue University Indianapolis (IUPUI) / The need for a safe but effective agent to sedate dental patients
who are severe behavior management problems prompted this investigation
of ketamine HCl. Ketamine HCl is a general anesthetic agent
with the unique property of selectively depressing the higher centers
of the brain without adversely affecting respiration or cardiac output.
Sixty behavior problem pedodontic patients were selected at
random and placed in one of three groups to receive the following
treatments: Treatment I - ketamine HCl and scopolamine; Treatment
II - ketamine, scopolamine, and droperidol, and Treatment III -
ketamine, scopolamine, and nitrous oxide-oxygen analgesia.
Each treatment group received ketamine HCl 2 mg/lb and 0.1 -
0.3 mg scopolamine. The second two treatment groups were supplemented
with droperidol .025 mg/lb or nitrous oxide-oxygen (20-50%)
to maintain anesthesia.
The patients were given a series of pre and post-treatment mental
and physical tests and were considered completely recovered when they
could equal their pre treatment test scores. Routine dental restorative
procedures limited to one and one-half hours were carried out with the
use of the ruber dam.
Onset of anesthesia was five minutes for all three treatment
groups. Treatment III showed a significantly longer working time but
recovery times were not significantly different between groups. Ketamine
HCl was determined to be a safe, effective agent for use in pedodontic
outpatients provided prescribed techniques are followed. Complications
were infrequent and minor and parental response was considered
satisfactory.
| Identifer | oai:union.ndltd.org:IUPUI/oai:scholarworks.iupui.edu:1805/3709 |
| Date | January 1973 |
| Creators | O'Brien, Daniel N., 1945- |
| Contributors | Roche, James R. |
| Source Sets | Indiana University-Purdue University Indianapolis |
| Language | en_US |
| Detected Language | English |
| Type | Thesis |
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