Obstructive sleep apnea (OSA) is a disease process characterized by collapse of the upper airway during periods of sleep leading to the cessation airflow despite persistent respiratory efforts. The aim of this research project is to investigate for associations and correlations between OSA and other clinical entities using two separate prospective studies. The initial objective was to evaluate the prevalence of laryngopharyngeal reflux (LPR) in patients with OSA. LPR was present in 26/28 (93%) of OSA patients. Moreover, there were significant correlations between LPR and OSA severity (eg. r = 0.57, p = 0.001). The second objective of this research study was to determine the prevalence of OSA in patients with cancer of the oral cavity and oropharynx, and to correlate the presence of OSA and the occurrence of postoperative morbidities. OSA was present in 76% of patients. Overall, postoperative complications were observed in 67% of OSA and 25% of non-OSA patients, although this difference was not yet significant (p = 0.27, Fisher exact test).
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.82403 |
| Date | January 2004 |
| Creators | Payne, Richard J., 1973- |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science (Department of Otolaryngology.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 002201470, proquestno: AAIMR12518, Theses scanned by UMI/ProQuest. |
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