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The effects of lesions to the superior colliculus and ventromedial thalamus on [kappa]-opioid-mediated locomotor activity in the preweanling rat

The purpose of this thesis was to determine the neuronal circuitry mediating U50,488-induced locomotion in preweanling rats. To this end, preweanling rats received bilateral electrolytic lesions of the ventromedial thalamus or superior colliculus and, two days later, the same rats received a challenge injection of U50,488. It was predicted that bilateral lesions of the ventromedial thalamus or superior colliculus would attenuate the U50,488-induced locomotor activity of 18-day-old rats.

Identiferoai:union.ndltd.org:csusb.edu/oai:scholarworks.lib.csusb.edu:etd-project-3405
Date01 January 2003
CreatorsZavala, Arturo Rubin
PublisherCSUSB ScholarWorks
Source SetsCalifornia State University San Bernardino
Detected LanguageEnglish
Typetext
Formatapplication/pdf
SourceTheses Digitization Project

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