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Investigation of the role of anterior and lateral connections of the ventromedial hypothalamus in control of food intake, activity, food motivation and reactivity to taste

The "hyperphagic syndrome" consists of a number of behavioral changes which normally occur along with the increased weight gain following
VMH lesions in the rat. The present study explored the possibility of separating these behavioral changes from the increased weight gain. The behavioral dimensions sampled were activity, tendency to work for food and reactivity to diet adulteration. Three different methods were employed to produce the increased weight gain: electrolytic VMH lesions, cuts lateral to the VMH, and cuts anterior to the VMH. The results confirmed
the decreased activity, decreased tendency to work for food, and increased reactivity to taste manipulation previously reported for VMH-lesioned animals. Cuts lateral to the VMH were indistinguishable from lesions on each of these measures. Cuts anterior to the VMH resulted in no change in normal activity level or in the tendency to work for food but did result in increased reactivity to taste manipulation. The results are consistent with the notion of a medial-lateral system controlling some facit of energy balance and of an anterior system underlying a sex dependent part of the weight gain in female rats. / Arts, Faculty of / Psychology, Department of / Graduate

Identiferoai:union.ndltd.org:UBC/oai:circle.library.ubc.ca:2429/34657
Date January 1971
CreatorsStorlien, Leonard Henry
PublisherUniversity of British Columbia
Source SetsUniversity of British Columbia
LanguageEnglish
Detected LanguageEnglish
TypeText, Thesis/Dissertation
RightsFor non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use.

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