nÃo hà / Este trabalho buscou comparar a eficÃcia anti-cÃrie e antimicrobiana de quatro diferentes substÃncias: carvacrol 20% (CAR), carvacrol 10% em associaÃÃo com o timol a 10% (CAR+THY), clorexidina a 20% (CHX) e fluoreto de sÃdio a 5% (NaF), em crianÃas de alto risco e livres de cÃrie. Cento e vinte crianÃas, entre 36 a 71 meses, foram selecionadas de prÃ-escolas pÃblicas de um bairro do MunicÃpio de Fortaleza (CearÃ), caracterizando-as segundo os critÃrios de risco à carie da Academia Americana de Odontologia PediÃtrica como crianÃas de alto risco. Essas crianÃas foram randomicamente distribuÃdas nos quatro grupos de tratamento. Os antimicrobianos foram manipulados na forma de verniz e aplicados trimestralmente durante um ano. Pacientes foram monitorados trimestralmente, atravÃs de exames clÃnicos periÃdicos para avaliaÃÃo do surgimento de lesÃes de cÃrie. Foram coletadas salivas antes do inÃcio do tratamento (B), apÃs 7 (D7), 30 (D30), 90 (D90), 180 (D180) e 360 (D360) dias de tratamento para detecÃÃo de EGM. Na anÃlise microbiolÃgica as amostras foram cultivadas sobre Agar MSB, incubadas em estufa a 37 C, com atmosfera de microaerofilia, durante 48 horas. As colÃnias foram confirmadas como sendo EGM a partir de provas bioquÃmicas. A contagem bacteriana foi expressa em unidades formadoras de colÃnias (UFC/mL). Dados foram considerados significativos quando p<0.02. Ao comparar os nÃveis de EGM entre B e D7 nÃo observou-se diferenÃa entre os tratamentos (p=0,032). ComparaÃÃes dos percentuais de reduÃÃo de EGM entre os grupos (D30-D90) e demonstrou uma diferenÃa estatisticamente significativa (p=0,002) , havendo diferenÃa entre o CAR versus CAR+THY (p=0,003); CAR +THY versus CHX (p=0,004) e CHX versus NaF, (p=0,014). O CAR+THY apresentou o menor percentual de reduÃÃo e a CHX o maior. Observamos um aumento de EGM nos grupos tratados com CHX e NaF em D360. ComparaÃÃes entre o ceo-s dentro de cada grupo, demonstrou uma diferenÃa significativa entre o ceo-s inicial e o ceo-s do exame realizado 9 meses apÃs o inÃcio dos tratamentos, com exceÃÃo do grupo NaF. Observou-se uma correlaÃÃo positiva significante entre o total de superfÃcies e a idade em todos os tratamentos estudados. NÃo houve diferenÃa significante da densidade de cÃrie entre as vÃrias faixas etÃrias dentro e entre os grupos. NÃo houve diferenÃa no ceo-s entre os grupos (p=0,746). Em conclusÃo, todos os tratamentos produziram significante reduÃÃo de EGM com grandes variaÃÃes dentro e entre os grupos, associada a baixa experiÃncia de cÃrie. / This study aimed to compare the anticaries and antimicrobial efficacy of four different substances: 20% carvacrol (CAR), 10% carvacrol in association with 10% thymol (CAR+THY), 20% chlorhexidine (CHX) and 5% sodium fluoride (NaF), in high-risk, caries-free children. One hundred and twenty children, between 36 and 71-months age, were selected from public preschools from a neighborhood in Fortaleza (CearÃ). Children were classified as a high caries-risk group according to the American Academy of Pediatric Dentistry Guidelines. These children were randomly allocated into four different treatment groups. Antimicrobial agents were made as varnishes and applied every 3 months, during one year. Patients were monitored every 3 months for new caries lesions. Saliva was collected before treatment initiation (B) and after 7 (D7), 30 (D30), 90 (D90), 180 (D180) and 360 (D360) days post-treatment for MS detection. For microbiological analysis, samples were cultivated on MSB agar media and incubated at 37o C under microaerofilic conditions, during 48 hours. Bacterial colonies were confirmed as being MS through biochemical tests. MS counts were expressed in colony forming units (CFU/mL). Data was considered significant when p<0.02. When comparing MS levels between B and D7, no difference was observed between groups (p=0,032). Comparisons of the percentage MS reduction between groups (D30-D90) demonstrated a significant difference (p=0,002), with a difference between CAR versus CAR+THY (p=0.003), CAR+THY versus CHX (p=0.004), and CHX versus NaF (p=0.014). CAR+THY presented the smallest percentage reduction, while CHX presented the greatest. We observed an increase in MS in the groups treated with CHX and NaF at D360. With the exception of the NaF group, comparisons between dmfs within each group, demonstrated a significant difference between the initial dmfs and the dmfs measured 9 months after treatment initiation. A significant positive correlation between the total dental surfaces and the patientâs age was observed in all groups. No significant difference was found between caries density of the different age groups within and between groups. The dmfs scores did not differ between groups (p=0,746). In conclusion, all treatments produced significant MS reduction with great variations within and between groups, associated with low caries experience.
| Identifer | oai:union.ndltd.org:IBICT/oai:www.teses.ufc.br:3837 |
| Date | 27 October 2010 |
| Creators | Jorgeana AbrahÃo Barroso |
| Contributors | Cristiane SÃ Roriz Fonteles |
| Publisher | Universidade Federal do CearÃ, Programa de PÃs-GraduaÃÃo em Odontologia, UFC, BR |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da UFC, instname:Universidade Federal do Ceará, instacron:UFC |
| Rights | info:eu-repo/semantics/openAccess |
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