Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents

Description

No / Several Ru-arene and Ir–Cp* complexes have been prepared
incorporating (N,N), (N,O) and (O,O) coordinating bidentate
ligands and have been found to be active against both HT-29
and MCF-7 cell lines. By incorporating a biologically active
ligand into a metal complex the anti-cancer activity is
increased.

Links & Downloads

1. Lucas SJ, Lord RM, Wilson RL, Phillips RM, Sridharan V and McGowan PC (2012) Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents. Dalton Transactions. 41: 13800.
2. http://hdl.handle.net/10454/9493
3. https://doi.org/10.1039/c2dt32104a

Tags

Iridium complexes

Ruthenium complexes

Anti-cancer agents

Additional Fields

Identifer	oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/9493
Date	07 December 2012
Creators	Lucas, S.J., Lord, Rianne M., Wilson, R.L., Phillips, Roger M., Sridharan, V., McGowan, P.C.
Source Sets	Bradford Scholars
Language	English
Detected Language	English
Type	Article, No full-text in the repository