Herein we describe the synthesis of (±) platensimycin, a potent antibiotic against gram-positive bacteria. The first chapter reviews (±) platensimycin’s isolation, biological profile and previously reported studies relevant to the area. The second chapter describes our initial efforts to synthesize (±) platensimycin. The third chapter accounts our second generation synthesis and its completion. The fourth chapter entails the experimental details of the important compounds in our synthesis. / text
| Identifer | oai:union.ndltd.org:UTEXAS/oai:repositories.lib.utexas.edu:2152/ETD-UT-2011-12-4421 |
| Date | 27 January 2012 |
| Creators | Rivera, Heriberto |
| Source Sets | University of Texas |
| Language | English |
| Detected Language | English |
| Type | thesis |
| Format | application/pdf |
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