The recent boom of Machine Learning Network Architectures like Generative
Adversarial Networks (GAN), Deep Convolution Generative Adversarial Networks
(DCGAN), Self Attention Generative Adversarial Networks (SAGAN), Context
Conditional Generative Adversarial Networks (CCGAN) and the development of
high-performance computing for big data analysis has the potential to be highly
beneficial in many domains and fittingly in the early detection of chronic diseases.
The clinical heterogeneity of one such chronic auto-immune disease like Systemic
Lupus Erythematosus (SLE), also known as Lupus, makes it difficult for medical
diagnostics. One major concern is a limited dataset that is available for diagnostics.
In this research, we demonstrate the application of Generative Adversarial Networks
for data augmentation and improving the error rates of Convolution Neural
Networks (CNN). Limited Lupus dataset of 30 typical ’butterfly rash’ images is used
as a model to decrease the error rates of a widely accepted CNN architecture like
Le-Net. For the Lupus dataset, it can be seen that there is a 73.22% decrease in the
error rates of Le-Net. Therefore such an approach can be extended to most recent
Neural Network classifiers like ResNet. Additionally, a human perceptual study
reveals that the artificial images generated from CCGAN are preferred to closely
resemble real Lupus images over the artificial images generated from SAGAN and
DCGAN by 45 Amazon MTurk participants. These participants are identified as
’healthcare professionals’ in the Amazon MTurk platform. This research aims to
help reduce the time in detection and treatment of Lupus which usually takes 6 to 9
months from its onset.
| Identifer | oai:union.ndltd.org:purdue.edu/oai:figshare.com:article/9631892 |
| Date | 16 October 2019 |
| Creators | Pradeep Periasamy (7242737) |
| Source Sets | Purdue University |
| Detected Language | English |
| Type | Text, Thesis |
| Rights | CC BY 4.0 |
| Relation | https://figshare.com/articles/Generative_Adversarial_Networks_for_Lupus_Diagnostics/9631892 |
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