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Attentional bias retraining in cigarette smokers attempting smoking cessation (ARTS): study protocol for a double blind randomised controlled trial

Yes / Smokers attend preferentially to cigarettes and other smoking-related cues in the environment, in what is
known as an attentional bias. There is evidence that attentional bias may contribute to craving and failure to stop smoking.
Attentional retraining procedures have been used in laboratory studies to train smokers to reduce attentional bias, although
these procedures have not been applied in smoking cessation programmes. This trial will examine the efficacy of multiple
sessions of attentional retraining on attentional bias, craving, and abstinence in smokers attempting cessation.
This is a double-blind randomised controlled trial. Adult smokers attending a 7-session weekly stop
smoking clinic will be randomised to either a modified visual probe task with attentional retraining or placebo training.
Training will start 1 week prior to quit day and be given weekly for 5 sessions. Both groups will receive 21 mg transdermal
nicotine patches for 8–12 weeks and withdrawal-orientated behavioural support for 7 sessions. Primary outcome measures
are the change in attentional bias reaction time and urge to smoke on the Mood and Physical Symptoms Scale at 4 weeks
post-quit. Secondary outcome measures include differences in withdrawal, time to first lapse and prolonged abstinence at
4 weeks post-quit, which will be biochemically validated at each clinic visit. Follow-up will take place at 8 weeks, 3 months
and 6 months post-quit.
This is the first randomised controlled trial of attentional retraining in smokers attempting cessation.
This trial could provide proof of principle for a treatment aimed at a fundamental cause of addiction. / National Institute for Health Research (NIHR) Doctoral Research Fellowship (DRF) awarded to RB (DRF-2009-02-15)

Identiferoai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/9777
Date January 2013
CreatorsBegh, R., Munafò, M.R., Shiffman, S., Ferguson, S.G., Nichols, L., Mohammed, Mohammed A., Holder, R.L., Sutton, S., Aveyard, P.
Source SetsBradford Scholars
LanguageEnglish
Detected LanguageEnglish
TypeArticle, Published version
Rights© 2013 Begh et al. This is an Open Access article distributed under the terms of the Creative Commons CC-BY License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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