Within the last decade, magnetic resonance imaging (MRI) scanners with ultra-high magnetic field strengths of 7 Tesla and above have become available. While high magnetic fields provide theoretical improvements in the nuclear magnetic resonance signal-to-noise ratio (SNR) and in the blood-oxygenation-level dependent (BOLD) contrast used for functional brain imaging, they also introduce technical issues such as increased bulk magnetic susceptibility effects and increased physiological noise in human data. Acquiring MRI data with multiple receiver coils in parallel can alleviate some of these issues at a cost to SNR and BOLD sensitivity that depends on several experiment-specific factors. This work attempts to address some of the issues surrounding high field fMRI in the context of parallel imaging and suggests methods for realizing the theoretical benefits of functional MRI with high magnetic fields.
| Identifer | oai:union.ndltd.org:VANDERBILT/oai:VANDERBILTETD:etd-03092010-161214 |
| Date | 15 March 2010 |
| Creators | Sexton, John Andrew |
| Contributors | Victoria L. Morgan, Rene M. Marois, Adam W. Anderson, J. Christopher Gatenby, John C. Gore |
| Publisher | VANDERBILT |
| Source Sets | Vanderbilt University Theses |
| Language | English |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | http://etd.library.vanderbilt.edu/available/etd-03092010-161214/ |
| Rights | unrestricted, I hereby certify that, if appropriate, I have obtained and attached hereto a written permission statement from the owner(s) of each third party copyrighted matter to be included in my thesis, dissertation, or project report, allowing distribution as specified below. I certify that the version I submitted is the same as that approved by my advisory committee. I hereby grant to Vanderbilt University or its agents the non-exclusive license to archive and make accessible, under the conditions specified below, my thesis, dissertation, or project report in whole or in part in all forms of media, now or hereafter known. I retain all other ownership rights to the copyright of the thesis, dissertation or project report. I also retain the right to use in future works (such as articles or books) all or part of this thesis, dissertation, or project report. |
Page generated in 0.0018 seconds