In 1947 a mould was found growing as a contaminant on a Lowenstein's slope which had been inoculated with sputum for the isolation of Mycobacterium tuberculosis which was found to produce, in addition to an antibiotic probably identical with penicillin, a substance capable of neutralizing various bacterial exotoxins. (Diena, 1954, 1956; Murray, Denton, Stevenson and Diena, 1958). The mould was identified as Penicillium cyaneo-fulvum and the toxin neutralizing substance was designated noxiversin. Noxiversin was shown to possess, in addition to its antitoxic properties, some activity against influenza virus (Diena, 1956).
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.113363 |
| Date | January 1961 |
| Creators | Cooke, Patricia. M. |
| Contributors | Stevenson, J. (Supervisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Doctor of Philosophy. (Department of Biology.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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