Previous work in this department by the present author and others, has demonstrated that changes accompanying the acquisition of resistance to chloramphenicol in Salmonella indicate structural changes in the surface of resistant organisms. Similar changes have been reported by other workers investigating both gram-positive and gram-negative chloramphenicol resistant organisms. The additional observation of a simultaneous increase in resistance to other antibiotics such as penicillin implies a possible non-specific mechanism contributing to resistance linked to the relative permeabilities of the cells. Work was therefore continued with a resistant strain of Salmonella typhimurium in an attempt to find out more about the mechanism of resistance.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.115503 |
| Date | January 1964 |
| Creators | Gill, Peter. |
| Contributors | Stevenson, J. (Supervisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Doctor of Philosophy. (Department of Biology.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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