Tumor bearing mice pre-treated with autochthonous and syngeneic inocula were found to have an enhanced immune response. Mitotic indices of the tumors from three experimental groups were significantly lower than those of the two control groups. The treated control group which received Freund's adjuvant also had a significantly lowered mitotic index, but was still significantly higher than the three experimental groups.The immune response was evidenced by reticuloendothelial involvement and anaphylactic reactions in various animals. Abnormalities found in the livers consisting of portal infiltration of reticular calls and megakaryocytes were observed. The tumor sections observed showed increased lymphocytic infiltration,There were no significant differences in the mitotic indices between the syngeneic and autochthonous recipients. A lack of antigenic differences in the tumors utilized is thus indicative of this finding.Ball State UniversityMuncie, IN 47306
| Identifer | oai:union.ndltd.org:BSU/oai:cardinalscholar.bsu.edu:handle/179945 |
| Date | 03 June 2011 |
| Creators | Stovall, William E. |
| Contributors | Rosene, Gordon L. |
| Source Sets | Ball State University |
| Detected Language | English |
| Format | iv, 54 leaves : ill. ; 28 cm. |
| Source | Virtual Press |
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