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Antibiotic resistance in Bartonella bacilliformis clinical isolates from an endemic area of Peru

Bartonella bacilliformis is a facultative, intracellular, aerobic, Gram-negative coccobacillus causing the so-called Carrión's disease, a human infection endemic to specific areas mainly inhabited by low-income communities of Peru but also present in other Andean communities. It is considered a truly neglected tropical disease and is transmitted through the bite of female sandflies of the genus Lutzomyia [1]. Carrión's disease has two different clinical presentations; an initial febrile and haemolytic anaemia phase, known as Oroya fever, which has a mortality rate ranging from 44% to 88% in untreated patients; and a second phase characterised by the development of dermal eruptions known as Peruvian wart [1,2]. / The study was supported by internal funds from the Universidad Peruana
de Ciencias Aplicadas (Lima, Peru); by a grant from the Instituto de Salud Carlos III,
Spain [PI11/00983], which included FEDER funds; by the UBS Optimus Foundation;
and by Generalitat de Catalunya, Departament d’Universitats, Recerca i Societat de
la Informació [2014 SGR 26]. MJP has received a postdoctoral fellowship from
CONCYTEC/FONDECYT. JR has received a fellowship from the program I3 of the
ISCIII [grant no. CES11/012]. / Revisión por pares

Identiferoai:union.ndltd.org:PERUUPC/oai:repositorioacademico.upc.edu.pe:10757/579762
Date15 October 2015
CreatorsSilva Caso, Wilmer, J. Ruiz, Del Valle Mendoza, Juana, Pons, Maria J
PublisherElsevier B.V.
Source SetsUniversidad Peruana de Ciencias Aplicadas (UPC)
LanguageEnglish
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/article
Formatapplication/pdf
SourceUniversidad Peruana de Ciencias Aplicadas (UPC), Repositorio Académico - UPC
Rightsinfo:eu-repo/semantics/openAccess
Relationhttp://www.jgaronline.com/article/S2213-7165(15)00060-0/references

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