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Protinádorová imunoterapie založená na instalaci manózy na povrch nádorových buněk / Anticancer immunotherapy based on the installation of mannose on the surface of tumor cells

The aim of this thesis was to find optimal therapy based on combination of membrane-anchored phagocytic ligands (mannose-(G)5-(K)10-STE, mannan-BAM, mannan-SMCC) with LPS (ligand of signal receptor)for treatment of murine melanoma B16-F10. Mixture of mannan-BAM with LPS applied in pulse regime proved to be the most effective, resulting in heigh reduction of tumor growth and significant prolongation of survival.

Identiferoai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:135738
Date January 2012
CreatorsMAIEROVÁ, Veronika
Source SetsCzech ETDs
LanguageCzech
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/masterThesis
Rightsinfo:eu-repo/semantics/restrictedAccess

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