The shape of a tissue or entire organ is important for its biological function. Tissue and organ shapes arise from molecular activities that control and execute cellular processes, such as oriented cell divisions, cell shape changes or cell rearrangements. However, how molecular activities control cellular processes during the shaping of organs is not well understood. This thesis spotlights two aspects of organ shaping based on Drosophila egg chambers as model tissue. One focus lies on three-dimensional imaging of cellular mechanics during development and the other aspect dissects the molecular function of the fat2 gene, that is crucial for tissue elongation in Drosophila egg chambers.:TABLE OF CONTENTS
1 SUMMARY ................................................................................................................... I
2 ZUSAMMENFASSUNG ...............................................................................................III
3 TABLE OF CONTENTS ................................................................................................V
4 LISTS ..........................................................................................................................10
5 INTRODUCTION ........................................................................................................16
6 AIMS OF THE THESIS ...............................................................................................40
7 MATERIALS AND METHODS .....................................................................................41
8 RESULTS ....................................................................................................................58
9 DISCUSSION .............................................................................................................92
10 ACKNOWLEDGEMENTS .......................................................................................103
11 REFERENCES ........................................................................................................105
12 APPENDIX ..............................................................................................................118
13 ERKLÄRUNG ..........................................................................................................123
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:75938 |
| Date | 10 September 2021 |
| Creators | Purkert, Sonja |
| Contributors | Dahmann, Christian, Reinhardt, Klaus, Technische Universität Dresden |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, doc-type:doctoralThesis, info:eu-repo/semantics/doctoralThesis, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
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