Anatomically, the stomach-proper of the adult mouse is composed of two parts, the corpus and pyloric antrum. By serially sectioning entire stomachs, and histologically reconstructing the stomach-proper, it has been shown that both areas contain numerous finger-like, epithelial infoldings or gastric units. Special attention was given to the units of the antrum, which by three-dimensional reconstruction appeared as tubes, generally having a single pit, a gland and connecting these an isthmus. Using light and electron microscopy, with or without ('3)H-thymidine radioautography, the renewal of gland cells was investigated. The mucous cells, making up about 82% of the gland cells were produced by the division of cells in the isthmus and upper gland, and displayed immature features. With time, mucous gland cells migrated toward the base of the gland, and began to assume the features of differentiated cells. Not all mucous gland cells, however, reached the gland base. Some were lost by cell death and phagocytosed by neighbouring cells, at various levels of the gland. While some mucous gland cells had a fairly short lifespan of several or more days, a few lived in excess of 60 days.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.71885 |
| Date | January 1983 |
| Creators | Lee, Eunice R. |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Doctor of Philosophy (Department of Anatomy.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 000187071, proquestno: AAINK66622, Theses scanned by UMI/ProQuest. |
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