Six male subjects underwent two levels of sodium deprivation to determine the effects of restricted sodium intake on arterial pressure and maximum oxygen uptake. Seven days of restricted sodium intake (63 mEq/day) resulted in significant increases in plasma renin and serum sodium concentration with accompanied decreases in blood volume, urine sodium concentration and arterial pressure. Maximum oxygen uptake did not change significantly as a result of the restricted sodium intake. Further restrictions in sodium ingestion (20 mEq/day) resulted in a greater renal retention of sodium without an apparent effect on blood volume, arterial pressure or maximum oxygen uptake. Continued restriction on sodium ingestion (63 mEq/day) beyond a seven day period eventually resulted in an adaptation response in plasma renin and blood volume. Plasma renin and blood volume returned toward pre-study levels with the continued administration of low sodium while arterial pressure remained depressed. Results of the study indicate that the treatment of hypertension with diets low in sodium resulted in a significant decrease in blood volume and arterial pressure without adversely affecting maximum oxygen uptake. / Source: Dissertation Abstracts International, Volume: 46-09, Section: B, page: 2967. / Thesis (Ph.D.)--The Florida State University, 1985.
| Identifer | oai:union.ndltd.org:fsu.edu/oai:fsu.digital.flvc.org:fsu_75663 |
| Contributors | O'LOUGHLIN, JAMES FRANCIS., Florida State University |
| Source Sets | Florida State University |
| Detected Language | English |
| Type | Text |
| Format | 152 p. |
| Rights | On campus use only. |
| Relation | Dissertation Abstracts International |
Page generated in 0.0147 seconds