Defective alkanethiol monolayers were studied as a model system to understand the stress changes observed in microcantilever-based DNA hybridization experiments. An exponential relationship between defect density and surface stress was found by performing simultaneous electrochemical/stress-sensing experiments. Microcantilevers with a range of defective alkylthiol self assembled monolayers were prepared and stress change/electrochemical data were collected in perchlorate, chloride, and bromide-containing electrolytes. Defects were probed using a ferrocene-thiol labeling technique which provides quantitative measurement of defect area. Using defects and solutions containing charge transferring adsorbates is suggested as a method for enhancing the surface stress signals in cantilever sensor systems. The best response from this study was obtained in bromide, as its exponential function had the sharpest increase with defect density.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.101628 |
| Date | January 2006 |
| Creators | Monga, Tanya. |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science (Department of Chemistry.) |
| Rights | © Tanya Monga, 2006 |
| Relation | alephsysno: 002593692, proquestno: AAIMR32756, Theses scanned by UMI/ProQuest. |
Page generated in 0.0248 seconds