This thesis describes techniques for performing calculations of absorbed dose conversion factors for therapeutic kilovoltage and megavoltage x-ray beams, by application of the Monte Carlo method. These factors are low-energy x-ray backscatter factors, B, low- and medium-energy x-ray mass energy absorption coefficient ratios, water-to-air, We,IP)w.a,r ' and megavoltage x-ray stopping power ratios, water-to-air, s. The EGS4 and ITS Monte Carlo systems were used to model the relevant particle transport. Consistent theoretical expressions for absorbed dose in kilovoltage x-ray beams have been proposed. For low-energy x-rays, the expression for absorbed dose to water, D, requires values of defined as a water kerma ratio at the surface of a water phantom, and also of [(Jie,,/P)w.,r]p, evaluated over the primary spectrum (free-in-air). For medium-energy O x-rays, values of (Pen(Z,f)I'P)w,air are necessary, which are dependent on depth, z, and field-size,f. Bragg-Gray cavity theory entails values of SWthI(z) to convert readings from recommended ionisation chambers, calibrated in terms of air-kerma or exposure, into D. Bremsstrahlung spectra have been calculated by detailed Monte Carlo simulations of the NPL standard accelerator, a Philips SL series linac and a Siemens Stabilipan x-ray unit. Values of (i1 ,,/P)w air and B' have been calculated for therapeutic polyenergetic kilovoltage beams, over a comprehensive range of field sizes and beam qualities, following the Monte Carlo calculation of photon fluence in water and by a kerma-weighted averaging technique utilising primary fluence spectra and pre-calculated values of monoenergetic Values of Spencer-Attix s,, have similarly been calculated for the NPL standard and therapeutic linac beams following the Monte Carlo calculation of electron fluence in water and by a dose-weighted averaging technique utilising primary fluence spectra and pre-calculated monoenergetic dose distributions. Accurate TPR values, which account for linac spectrum quality shift off-axis, have been acquired by convolving water terma distributions with point-energy-deposition kernels. The beam quality dependence of N, the NFL absorbed dose-to-water calibration factor, has subsequently been investigated. Data appropriate for insertion into recommended expressions for D is presented and compared to data provided in the literature.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:389910 |
| Date | January 1996 |
| Creators | Knight, Richard Thomas |
| Publisher | Institute of Cancer Research (University Of London) |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
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