A range of conjugates which focused on bisphosphonates as delivery molecules and on oestrogens as resorption inhibitors were synthesised. Various moieties were coupled through an ester linkage to bisphosphonates which were then converted to the corresponding bisphosphonic acids. This ester linkage was considered to be readily hydrolysable under normal physiological conditions.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:324504 |
| Date | January 1999 |
| Creators | Mansfield, Ian David |
| Publisher | Loughborough University |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Source | https://dspace.lboro.ac.uk/2134/27412 |
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