This master thesis deals with the contrast agents and their application in the ultrasound perfusion analysis. It is focused on Bolus & Burst method which, as a combination of two approaches that have been used so far, allows an absolute quantification of perfusion parameters in the region of interest. Contrast agent concentration time sequence is modeled as a convolution of the parametrically defined arterial input function and the tissue residual funkction. Thesis discusses different mathematical models of these functions as well as the methods of the parameters estimation. The methods functionality is validated on simulated and also preclinical data.
| Identifer | oai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:316816 |
| Date | January 2017 |
| Creators | Jakubík, Juraj |
| Contributors | Jiřík, Radovan, Mézl, Martin |
| Publisher | Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií |
| Source Sets | Czech ETDs |
| Language | Czech |
| Detected Language | English |
| Type | info:eu-repo/semantics/masterThesis |
| Rights | info:eu-repo/semantics/restrictedAccess |
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