A non-invasive, in vitro method of estimating mean pulmonary artery pressure (PAP) was developed. This information was obtained by establishing a relationship between the pneumatic right drive pressure (RDP) and PAP waveforms. The RDP-PAP relationship was formalized into a series of multiple-linear regression equations for TAH cardiac cycles of known fill volume (FV). Correlation of computed estimates of PAP to actual measurements showed that these equations were greater than 92% accurate within 1.84 mmHg. In addition, while the RDP-PAP relationships were wholly dependent on FV, it was shown that they are independent of the manner in which FV was obtained. This method proved useful over the clinical operating range of the pneumatic heart driver, as well as over the normal physiological range of PAP in the human. Effectiveness of this method in vivo needs to be demonstrated.
| Identifer | oai:union.ndltd.org:arizona.edu/oai:arizona.openrepository.com:10150/276785 |
| Date | January 1988 |
| Creators | Vonesh, Michael John, 1964- |
| Contributors | Mylrea, Kenneth C. |
| Publisher | The University of Arizona. |
| Source Sets | University of Arizona |
| Language | en_US |
| Detected Language | English |
| Type | text, Thesis-Reproduction (electronic) |
| Rights | Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author. |
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