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Interspecimen Study of Bone to Relate Macromechanical, Nanomechanical and Compositional Changes Across the Femoral Cortex of Bone

Mechanics of bone is widely studied and researched, mainly for the study of fracture. This has been done mostly on a macro scale. In this work hierarchical nature of bone has been explored to investigate bone mechanics in more detail. Flexural test were done to classify the bones according to their strength and deflection. Raman spectroscopy analysis was done to map the mineralization, collagen crosslinking changes across the thickness of the bone. Nanoindentation was done to map indentation hardness and indentation modulus across femoral cortex of the bone. The results indicate that the composition of the bone changes across the thickness of the femoral cortex. The hypothesis is confirmed as increase in mineralization, carbonate to phosphate ratio and collagen crosslinking shows the effect as increased indentation hardness and modulus and decreased deflection.

Identiferoai:union.ndltd.org:unt.edu/info:ark/67531/metadc271868
Date05 1900
CreatorsNar, Mangesh
ContributorsD'Souza, Nandika Anne, 1967-, Brostow, Witold, 1934-, Xia, Zhenhai, Mirshams, Reza, Dahotre, Narendra
PublisherUniversity of North Texas
Source SetsUniversity of North Texas
LanguageEnglish
Detected LanguageEnglish
TypeThesis or Dissertation
FormatText
RightsPublic, Nar, Mangesh, Copyright, Copyright is held by the author, unless otherwise noted. All rights Reserved.

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