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Optimizing fracture management: Correlating the physical and mechanical properties of bone to computed tomography to generate an estimate of bone quality

Non-invasive estimates of bone quality are of great interest as they could potentially improve the diagnosis and treatments for bone disorders, such as osteoporosis, and could aid in preoperative planning of surgical interventions, improving patient outcomes in orthopaedic trauma.
Quantitative computed tomography (QCT) is currently being investigated as a method of estimating structural bone mineral content (sBMC) and, thus, bone quality. However, the reported correlations between QCT and sBMC have been variable and the relationships reported between sBMC and the apparent elastic modulus (E*) of bone have been even more variable.
A series of investigations are presented, relating QCT, sBMC, apparent density and the E* of bone. These studies were performed with the ultimate objective of determining the appropriateness of QCT as a predictor of the E* of bone and whether the E* of bone could be predicted from information regarding the sBMC and apparent density. / Thesis (Master, Mechanical and Materials Engineering) -- Queen's University, 2008-01-31 22:00:08.77 / This work was funded by the Canadian Institutes of Health Research.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:OKQ.1974/1022
Date05 February 2008
CreatorsCrookshank, Meghan Cathleen Maria
ContributorsQueen's University (Kingston, Ont.). Theses (Queen's University (Kingston, Ont.))
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish, English
Detected LanguageEnglish
TypeThesis
Format2767035 bytes, application/pdf
RightsThis publication is made available by the authority of the copyright owner solely for the purpose of private study and research and may not be copied or reproduced except as permitted by the copyright laws without written authority from the copyright owner.
RelationCanadian theses

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