joruiz@clinic.ub.es / Objective: To characterize two Achromobacter xylosoxidans recovered from 2 patients diagnosed
with pertussis during a Bordetella pertussis surveillance program. Methods: Nasopharyngeal
swabs from 2 children under 1 year of age with clinical suspicion of pertussis were analyzed
by culture and PCR. Results: Two Achromobacter xylosoxidans A8, closely related to Bordetella
spp. were recovered from 2 patients diagnosed of pertussis, both carrying the ptxA gene and
IS418 the pertussis toxin encoding gene. Subsequently, antibiotic susceptibility was evaluated
by disk-diffusion method and by PCR. Conclusions: Although more detailed studies are
needed, the present data highlight the possibility that Achromobacter xylosoxidans, closely
related Bordetella pertussis microorganisms and not covered under the vaccine umbrella, might
also result in cases of whooping cough. Thereby further surveillance is necessary to determine
the extension and relevance of their pathogenic role in order to discriminate their real public
health implication.
| Identifer | oai:union.ndltd.org:PERUUPC/oai:repositorioacademico.upc.edu.pe:10757/554305 |
| Date | 20 May 2015 |
| Creators | Pons, Maria J., Gomes, Cl觃udia, Bada, Carlos, Reyes, Isabel, Del Valle Mendoza, Juana, Ruiz, Joaquim |
| Publisher | Elsevier B.V. |
| Source Sets | Universidad Peruana de Ciencias Aplicadas (UPC) |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/article |
| Source | Universidad Peruana de Ciencias Aplicadas (UPC), Repositorio Académico - UPC |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | https://www.researchgate.net/publication/276831508_Characterization_of_two_Achromobacter_xyloxosidans_isolates_from_patients_with_pertussis-like_symptoms |
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