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Tetracycline-7-boronic acid

The objective of this study is the preparation of a tetracycline-boron-10 derivative which is stable under biological conditions. The boron-10 should then provide a concentration of material capable of accepting thermal neutrons, thus producing localized high-energy alpha radiation. The fact that the tetracyclines are not retained by normal tissue should remove the danger of destruction of this tissue.

Identiferoai:union.ndltd.org:pacific.edu/oai:scholarlycommons.pacific.edu:uop_etds-1363
Date01 January 1960
CreatorsRhoads, William Denham
PublisherScholarly Commons
Source SetsUniversity of the Pacific
Detected LanguageEnglish
Typetext
Formatapplication/pdf
SourceUniversity of the Pacific Theses and Dissertations

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