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Enlargement of a Modular System—Synthesis and Characterization of an s-Triazine-Based Carboxylic Acid Ester Bearing a Galactopyranosyl Moiety and an Enormous Boron Load

The amount of boron accumulated in tumor tissue plays an important role regarding the
success of the boron neutron capture therapy (BNCT). In this article, we report a modular system,
combining readily available starting materials, like glycine, 1,3,5-triazine and the well-known
9-mercapto-1,7-dicarba-closo-dodecaborane(12), as well as alpha-d-galactopyranose for increased
hydrophilicity, with a novel boron-rich tris-meta-carboranyl thiol.

Identiferoai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:84653
Date11 April 2023
CreatorsKellert, Martin, Lönnecke, Peter, Riedl, Bernd, Koebberling, Johannes, Hey-Hawkins, Evamarie
PublisherMDPI
Source SetsHochschulschriftenserver (HSSS) der SLUB Dresden
LanguageEnglish
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text
Rightsinfo:eu-repo/semantics/openAccess
Relation1420-3049, 3288

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