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Citlivost spirochet komplexu \kur{Borrelia burgdorferi} sensu lato k lidskému komplementu: infekční potenciál vybraných druhů / Sensitivity of spirochetes from \kur{Borrelia burgdorferi} sensu lato complex to human complement: infection potential of selected species

Sensitivity of spirochetes from Borrelia burgdorferi sensu lato complex to serum complement of humans of different age and sex was analyzed. Complement-mediated Borrelia killing was observed in different combination of serum and selected Borrelia genospecies. The obtained results confirmed that age itself does not influence the sensitivity of human to Borrelia infection. However, the females seem to be more vulnerable to it. Each of ten tested Borrelia species was proved to be potentially infective for human in different ratio. The clear separation of all ten checked Borrelia species into two groups was revealed after the reaction with human sera: species with low sensitivity to human serum complement (mortality below 1 percent) and species with higher sensitivity (mortality over 3-4 percent).

Identiferoai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:201551
Date January 2015
CreatorsTICHÁ, Lucie
Source SetsCzech ETDs
LanguageCzech
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/masterThesis
Rightsinfo:eu-repo/semantics/restrictedAccess

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