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Joint Trajectories of Bullying Victimization and Perpetration: Investigating the Role of the COMT Gene

Bullying research has grown tremendously throughout the years, and yet, there is a lack of research investigating the biological underpinnings of bullying victimization and perpetration. The single nucleotide polymorphism catechol-O-methyltransferase (COMT) Val158Met is an important candidate gene that has been demonstrated to interact with environmental factors and play an important role in emotion processing. However, it remains unknown whether COMT Val158Met influences youth and adolescents’ involvement as both targets and perpetrators of bullying, considering bully-victims are found to struggle with emotion regulation. To address this knowledge gap, the role of COMT Val158Met on the joint trajectories of bullying victimization and perpetration was investigated in a longitudinal community sample. A latent class growth analysis (LCGA) was used to identify distinct patterns of bullying victimization and perpetration across the ages 10 to 18 years (n = 648). A three-class solution was chosen for bullying victimization where most participants were reflected in a trajectory of low decreasing bullying victimization (74%), followed by moderate stable trajectory of bullying victimization (23%) and a final group following a high stable trajectory of bullying victimization (3%). A two-class solution was chosen for bullying perpetration. As predicted, most participants were reflected in the low stable bullying perpetration group (83%) and a small group followed a moderate increasing/decreasing trajectory of bullying perpetration (16.4%). Dual trajectory models revealed distinct subgroup of individuals involved in bullying either as targets, perpetrators, or bully-victims. Conditional probabilities results suggest that highly victimized youth would in time perpetrate against others while remaining targets of high levels of perpetration (i.e., target to bully-victim), whereas youth moderately victimized were more likely to be uninvolved in bullying perpetration. There was no significant difference in allelic variations (i.e., any Met allele vs Val/Val) of COMT Val158Met between bully-victims and children uninvolved in bullying. Implications of these findings are discussed from a differential susceptibility model. Gaining an understanding of the mechanisms behind the impact of bullying victimization and perpetration on children and adolescent will help provide insight and support for school and clinical prevention and intervention efforts.

Identiferoai:union.ndltd.org:uottawa.ca/oai:ruor.uottawa.ca:10393/45452
Date22 September 2023
CreatorsDesmarais, Riley
ContributorsVaillancourt, Tracy
PublisherUniversité d'Ottawa / University of Ottawa
Source SetsUniversité d’Ottawa
LanguageEnglish
Detected LanguageEnglish
TypeThesis
Formatapplication/pdf

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