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Induction of Interferon Messenger RNA and Expression of Cellular Oncogenes in Human Lymphoblastoid Cells

The purposes of this study was to demonstrate the induction of alpha interferon mRNA in Sendai virus-induced Namalava cells, to follow the level of alpha interferon mRNA synthesis at the transcriptional level, and to determine whether the Namalava cell line expresses the c-myc oncogene and to what degree. The amount of c-myc message deteted in Namalva cell RNA was about one-tenth that of Daudi cell RNA, whereas no difference in the amount of the c-Ha-ras message was observed between the two cell lines.

Identiferoai:union.ndltd.org:unt.edu/info:ark/67531/metadc798199
Date12 1900
CreatorsMahmoudi, Massoud
ContributorsVela, G. Roland, 1927-, Johansson, Karl R., Schafer, Rollie, Norton, S. J.
PublisherNorth Texas State University
Source SetsUniversity of North Texas
LanguageEnglish
Detected LanguageEnglish
TypeThesis or Dissertation
Formatvii, 152 leaves : ill., Text
RightsPublic, Mahmoudi, Massoud., Copyright, Copyright is held by the author, unless otherwise noted. All rights

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