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Geographical Clusters, Alliance Network Structure, and Innovation in the US Biopharmaceutical Industry

I examine the effects of firms cluster membership on their alliance network structure, and how firms absorptive capacity moderates the relationship between alliance network structure and innovation. Little is known regarding the inter-relationship between cluster membership, network structure and innovation. This study bridges this gap by first establishing the endogenous nature of network structure with respect to cluster membership and then by studying the moderating effect of absorptive capacity for the alliance network structure and innovation relationship.
I contribute to the strategic management literature in several important ways. First, I clarify the implications of cluster membership on network structure by including two competing explanations: complementary and substitution mechanisms. Contrary to the popular belief that cluster membership does not matter, I find that it does matter in the study of the US biopharmaceutical industry. My findings show that firms location within a cluster area does not substitute for their strategic choices specifically for their alliance strategies. Second, I theoretically argue and then empirically demonstrate that network structure is an endogenous phenomenon with respect to cluster membership. Third, I demonstrate that when controlled for endogeneity with respect to cluster membership, alliance network structure and innovation relationship is positively moderated by firms absorptive capacity. In contrast to prior literature, I find that the main effect of firms structural holes on innovation is not significant when controlled for endogeneity. This finding is important given the mixed findings for structural holes and innovation relationship in previous studies. Finally, to the best of my knowledge, in the strategic management literature this study is the first study to introduce an exponential regression model with Generalized Methods of Moments (GMM) estimation that accounts for both the endogenous nature of independent variables and the count nature of dependent variable.

Identiferoai:union.ndltd.org:PITT/oai:PITTETD:etd-11062006-143723
Date17 May 2007
CreatorsCaner, Turanay
ContributorsSusan K. Cohen, Ph.D., John Hulland, Ph.D., Balaji Koka, Ph.D., Ravindranath Madhavan, Ph.D., John E. Prescott, Ph.D.
PublisherUniversity of Pittsburgh
Source SetsUniversity of Pittsburgh
LanguageEnglish
Detected LanguageEnglish
Typetext
Formatapplication/pdf
Sourcehttp://etd.library.pitt.edu/ETD/available/etd-11062006-143723/
Rightsunrestricted, I hereby certify that, if appropriate, I have obtained and attached hereto a written permission statement from the owner(s) of each third party copyrighted matter to be included in my thesis, dissertation, or project report, allowing distribution as specified below. I certify that the version I submitted is the same as that approved by my advisory committee. I hereby grant to University of Pittsburgh or its agents the non-exclusive license to archive and make accessible, under the conditions specified below, my thesis, dissertation, or project report in whole or in part in all forms of media, now or hereafter known. I retain all other ownership rights to the copyright of the thesis, dissertation or project report. I also retain the right to use in future works (such as articles or books) all or part of this thesis, dissertation, or project report.

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