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Nové modifikované 7-deazapurinové báze a nukleosidy / New modified 7-deazapurine bases and nucleosides

The three ways of synthesis of 5'-deoxy and 5'deoxy-5'-fluoromodified nucleosides derived from known cytostatic compounds was designed. Two routes were successfully developed and target substances were prepared. Third one was unsuccessful due to difficulties with deprotection of the key intermediate.

Identiferoai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:348670
Date January 2015
CreatorsKrömer, Matouš
ContributorsHocek, Michal, Smrček, Stanislav
Source SetsCzech ETDs
LanguageCzech
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/masterThesis
Rightsinfo:eu-repo/semantics/restrictedAccess

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