TfOH-catalyzed reaction of bispropargyl alcohols with 1,3-dicarbonyl compounds

Description

No / A transition-metal-free efficient method for the preparation of 1,2,3-trisubstituted benzenes from bispropargyl alcohols and 1,3-dicarbonyl compounds has been developed. The reaction of bispropargyl alcohol with 1,3-dicarbonyl compound proceeds through [3,3]-rearrangement, 6π-electrocyclization, and unexpected Csp3−Csp2 regioselective σ-bond cleavage processes.

Links & Downloads

1. Teng Q, Mo S, Pan J et al (2016) TfOH-catalyzed reaction of bispropargyl alcohols with 1,3-dicarbonyl compounds. Synthesis. 48(3): 455-461.
2. http://hdl.handle.net/10454/17870
3. https://doi.org/10.1055/s-0035-1560372

Tags

Bispropargyl alcohols

1

3-dicarbonyl compounds

[3

3]-rearrangement

C−C α′-moiety cleavage

6π-electrocyclization process

1

2

3-trisubstituted benzenes

Additional Fields

Identifer	oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/17870
Date	03 June 2020
Creators	Teng, Q., Mo, S., Pan, J., Wu, Na, Wang, H., Pan, Y.
Source Sets	Bradford Scholars
Language	English
Detected Language	English
Type	Article, No full-text in the repository