Return to search

Soluble Dectin-1 as a Tool to Detect β-Glucans

β-Glucans are structural components of fungal cell walls which are involved in the immune recognition of fungal pathogens and possess beneficial immunomodulatory activities in isolated form. Here we have developed a soluble chimeric form of the major mammalian β-glucan receptor, Dectin-1, and demonstrate its application for the detection and characterisation of soluble and insoluble β-glucans, including fungal particles, using ELISA, flow cytometric and fluorescence-based microscopy assays.

Identiferoai:union.ndltd.org:ETSU/oai:dc.etsu.edu:etsu-works-19364
Date31 July 2006
CreatorsGraham, Lisa, Tsoni, S. Vicky, Willment, Janet A., Williams, David L., Taylor, Philip R., Gordon, Siamon, Dennehy, Kevin, Brown, Gordon D.
PublisherDigital Commons @ East Tennessee State University
Source SetsEast Tennessee State University
Detected LanguageEnglish
Typetext
SourceETSU Faculty Works

Page generated in 0.0018 seconds