In first part we have developed a simple regiocontrolled protocol of
1,3-DC to get ring fused pyrazole derivatives. These pyrazole derivatives were synthesized using
1,3-DC between nitrile imine and various dipolarophiles such as alkynes, cyclic α,β-ketones,
lactones, thiocatones and lactums. The reactions were found to be highly regiospecific.
In second part we have discussed about helicene, its properties, synthesis and applications
as asymmetric catalyst.Due to inherent chirality, herein we have made an
attempt to synthesize the helicene-thiourea based catalyst for asymmetric catalysis. The synthesis
involved formation of two key intermediates viz, bromo-phenanthrene 5 and a vinyl-naphthalene
10. The coupling of these two intermediates leads to formation of hexahelicene.
| Identifer | oai:union.ndltd.org:unibo.it/oai:amsdottorato.cib.unibo.it:5826 |
| Date | 22 April 2013 |
| Creators | Chandanshive, Jay Zumbar <1983> |
| Contributors | Comes Franchini, Mauro |
| Publisher | Alma Mater Studiorum - Università di Bologna |
| Source Sets | Università di Bologna |
| Language | English |
| Detected Language | English |
| Type | Doctoral Thesis, PeerReviewed |
| Format | application/pdf |
| Rights | info:eu-repo/semantics/openAccess |
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