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Previous issue date: 2015-01-09 / O presente trabalho teve como objetivo analisar a resposta biol?gica em superf?cies de tit?nio
modificadas por plasma de Ar+N2+H2. Discos de tit?nio grau II receberam diferentes tratamentos
de superf?cie com plasma de Ar+N2+H2, constituindo sete grupos experimentais incluindo
amostras apenas polidas utilizadas como padr?o. Antes e ap?s o tratamento as amostras foram
caracterizadas quanto ? topografia, estrutura cristalina e molhabilidade, usando microscopia
de for?a at?mica, difra??o de raios-X, espectroscopia Raman e ensaio da gota s?ssil,
respectivamente. Plasma sangu?neo rico em plaquetas (PRP) foi aplicado sobre as superf?cies
modificadas em placas de cultivo. Imagens obtidas por microscopia eletr?nica das plaquetas
aderidas foram analisadas a fim de verificar o comportamento das plaquetas nas diferentes
condi??es experimentais. Verificou-se que a adi??o de H2 na atmosfera do plasma resultou em
superf?cies mais rugosas, com picos arredondados. Essas superf?cies, ao contr?rio daquelas
tratadas com atmosfera de alta concentra??o de N2, s?o menos propensas ? agrega??o
plaquet?ria e, consequentemente, ? forma??o de trombos quando aplicadas em dispositivos
biom?dicos. / This study aimed to analyze the biological response of titanium surfaces modified by plasma Ar + N2
+ H2. Titanium disks grade II received different surface treatments Ar + N2 + H2 plasma, constituting
seven groups including only polished samples used as standard. Before and after treatment the samples
were evaluated in terms of topography, crystal structure and wettability, using atomic force
microscopy, X-ray diffraction, Raman spectroscopy and testing of the sessile drop, respectively. Rich
plasma (PRP) was applied to the surfaces modified in culture plates. Images obtained by scanning
electron microscopy of the adhered platelets were analyzed to verify the behavior of platelets in the
different experimental conditions. We verified that the adition of H2 on plasma atmosphere resulted in
more rough surfaces, with round tops. These surfaces, in contrast to that surfaces treated with high
concentration of N2, are less propense to platelet aggregation and, consequently, to the formation of
thrombus when applied in biomedical devices.
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.ufrn.br:123456789/19686 |
| Date | 09 January 2015 |
| Creators | Vitoriano, Jussier de Oliveira |
| Contributors | 09621199468, http://lattes.cnpq.br/7441669258580942, Viana Neto, Bartolomeu Cruz, 03082297463, http://lattes.cnpq.br/2504557482950231, Farias, Naisandra Bezerra da Silva, 91439760420, Alves J?nior, Clodomiro |
| Publisher | Universidade Federal do Rio Grande do Norte, P?S-GRADUA??O EM ENGENHARIA MEC?NICA, UFRN, Brasil |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Source | reponame:Repositório Institucional da UFRN, instname:Universidade Federal do Rio Grande do Norte, instacron:UFRN |
| Rights | info:eu-repo/semantics/openAccess |
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