Macrophages (M?) are widely distributed immune cells and can be phenotypically polarised by microenvironment to mount specific functional programs. M? polarised in vitro can be broadly classified in two main groups: classically activated (or Ml), and alternatively activated (or M2) M?. M1 exhibit potent microbicidal properties and induce pro-inflammatory responses, whilst M2 play a role in resolution of inflammation and reduce pro-inflammatory responses.
Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:493453 |
Date | January 2008 |
Creators | Liu, Yu |
Publisher | University of Aberdeen |
Source Sets | Ethos UK |
Detected Language | English |
Type | Electronic Thesis or Dissertation |
Source | http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=24848 |
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