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Effect of cadmium on Ca2+ modulation and cytotoxicity in renal tubular cells

Cadmium (Cd2+) is a widely distributed industrial and environmental toxin , the
effect of Cd2+, a known nephrotoxicant, on intracellular free Ca2+ levels ([Ca2+]i) in
Madin Darby canine kidney (MDCK) cells was explored. [Ca2+]i was measured by
using the Ca2+-sensitive dye fura-2. Cd2+ increased [Ca2+]i in a concentrationdependent
manner with an EC50 of 38

Identiferoai:union.ndltd.org:NSYSU/oai:NSYSU:etd-0622106-211841
Date22 June 2006
CreatorsYeh, Mei-yin
ContributorsChen-fu Shaw, Chung-ren Jan, Jau-cheng Liou, David Chao
PublisherNSYSU
Source SetsNSYSU Electronic Thesis and Dissertation Archive
LanguageCholon
Detected LanguageEnglish
Typetext
Formatapplication/pdf
Sourcehttp://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0622106-211841
Rightsnot_available, Copyright information available at source archive

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