Pancreaic stem cells are potent to differentiate into insulin producing -cells. Stem cells would be use for the cell therapy in the future. This diploma thesis is focused on this four transcription factors (LIF, noggin, TGF- a BMP-2) and their effects on the differentiation of the pancreatic stem cells into -cells. The results were analysed by evidential methods (RT-PCR, immunofluorescence and static incubation.
| Identifer | oai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:280628 |
| Date | January 2010 |
| Creators | Leontovyč, Ivan |
| Contributors | Hodek, Petr, Lukšan, Ondřej |
| Source Sets | Czech ETDs |
| Language | Czech |
| Detected Language | English |
| Type | info:eu-repo/semantics/masterThesis |
| Rights | info:eu-repo/semantics/restrictedAccess |
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