Title page, table of contents and summary only. The complete thesis in print form is available from the University of Adelaide Library. / HIV-1 infection of astrocytes is involved in HIV-1 induced neurological diseases and is a possible source of viral persistence. In situ studies of post mortem brain tissue indicate that HIV-1 infection of astrocytes does occur, but is restricted. Previous in vitro studies have revealed intrinsic intracellular blocks to HIV-1 transcription and translation in astrocytes. The early viral replication steps of entry, reverse transcription and integration have not been previously characterised in detail in astrocytes, and are the focus of this study. / http://proxy.library.adelaide.edu.au/login?url= http://library.adelaide.edu.au/cgi-bin/Pwebrecon.cgi?BBID=1274468 / Thesis (Ph.D.) -- University of Adelaide, School of Molecular and Biomedical Science, 2007
Identifer | oai:union.ndltd.org:ADTP/286324 |
Date | January 2007 |
Creators | Clarke, Jennifer |
Source Sets | Australiasian Digital Theses Program |
Detected Language | English |
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