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An investigation of the role of N102 of the GnRH receptor in determining the potency of C-terminally modified agonist analogs

Bibliography : leaves 84-104. / Three GnRH receptors with the mutations N102A, N102D and N102K, which were derived from the human GnRH receptor by site directed mutagenesis, were expressed in COS-1 cells. The effects of these mutations on the potency of seven C-terminally modified GnRH agonist analogs for the stimulation of IP production were determined.

Identiferoai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uct/oai:localhost:11427/2692
Date January 2000
CreatorsHenshall-Howard, Marie-Paule Alix Emilie
ContributorsDavidson, James
PublisherUniversity of Cape Town, Faculty of Health Sciences, Division of Chemical Pathology
Source SetsSouth African National ETD Portal
LanguageEnglish
Detected LanguageEnglish
TypeMaster Thesis, Masters, MSc
Formatapplication/pdf

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