Goals of this study are to point out strategies to influence the gel-matrix building components of biofilms. One well characterised component of the extracellular polymeric substances (EPS) of the bacterial strain Pseudomonas aeruginosa SG81 is the alginate AlgSG81. AlgSG81 is one main component of EPS and thus of the gel-matrix, too. AlgSG81 is completely dissociated in aqueous solution and therefore a strong polyelectrolyte (PEL). By means of computation with OSF-theory and validation via viscosity measurements the conformation of AlgSG81-chains in aqueous solution at screened and not screened conditions is that of a coil over a large concentration regime. By addition of tetramethylurea (TMU) to aqueous solutions of AlgSG81 the formation of a physical network (gel) is observed. Different empirical and theoretical approaches to characterise PEL were improved and experimental verified.
| Identifer | oai:union.ndltd.org:DUETT/oai:DUETT:duett-09262003-135616 |
| Date | 01 October 2003 |
| Creators | Kenning, Arnd |
| Contributors | Prof. Dr. W. Borchard, Prof. Dr. C. Mayer |
| Publisher | Gerhard-Mercator-Universitaet Duisburg |
| Source Sets | Dissertations and other Documents of the Gerhard-Mercator-University Duisburg |
| Language | German |
| Detected Language | English |
| Type | text |
| Format | text/html, application/pdf |
| Source | http://www.ub.uni-duisburg.de/ETD-db/theses/available/duett-09262003-135616/ |
| Rights | unrestricted, I hereby certify that, if appropriate, I have obtained and attached hereto a written permission statement from the owner(s) of each third party copyrighted matter to be included in my thesis, dissertation, or project report, allowing distribution as specified below. I certify that the version I submitted is the same as that approved by my advisory committee. Hiermit erteile ich der Universitaet Duisburg das nicht-ausschliessliche Recht unter den unten angegebenen Bedingungen, meine Dissertation, Staatsexamens- oder Diplomarbeit, meinen Forschungs- oder Projektbericht zu veroeffentlichen und zu archivieren. Ich behalte das Urheberrecht und das Recht das Dokument zu veroeffentlichen und in anderen Arbeiten weiterzuverwenden. |
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