Pharmaceutical adjuvants or excipients are important ingredients of medicaments. These substances are used as support and for building the matrix for the active ingredients. In this way, the active ingredients will be realised in accurately and defined way at the specific site of action. In this study, the most important pharmaceutical adjuvants are characterised and analysed via near infrared-spectroscopic methods. The powdery samples were measured by means of diffuse reflectance with six NIR-spectrometer. The obtained NIR-spectra were used to build a near infrared spectra library based on SpecInfo systems of the firm Chemical Concepts. Furthermore, discrimination analysis were carried out, while reference spectra were compared with the database for performing an identity control.
| Identifer | oai:union.ndltd.org:DUETT/oai:DUETT:duett-12142005-142454 |
| Date | 19 December 2005 |
| Creators | Aschenbroich, Gregor |
| Contributors | Prof. Dr. Karl Molt, PD Dr. Evelin Denkhaus |
| Publisher | Gerhard-Mercator-Universitaet Duisburg |
| Source Sets | Dissertations and other Documents of the Gerhard-Mercator-University Duisburg |
| Language | German |
| Detected Language | English |
| Type | text |
| Format | application/pdf, text/html |
| Source | http://www.ub.uni-duisburg.de/ETD-db/theses/available/duett-12142005-142454/ |
| Rights | unrestricted, I hereby certify that, if appropriate, I have obtained and attached hereto a written permission statement from the owner(s) of each third party copyrighted matter to be included in my thesis, dissertation, or project report, allowing distribution as specified below. I certify that the version I submitted is the same as that approved by my advisory committee. Hiermit erteile ich der Universitaet Duisburg das nicht-ausschliessliche Recht unter den unten angegebenen Bedingungen, meine Dissertation, Staatsexamens- oder Diplomarbeit, meinen Forschungs- oder Projektbericht zu veroeffentlichen und zu archivieren. Ich behalte das Urheberrecht und das Recht das Dokument zu veroeffentlichen und in anderen Arbeiten weiterzuverwenden. |
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