The changes which occur in water absorbance in the near-infrared (NIR) region, specifically at 960 nm, are correlated to tissue temperature. One of the temperature-varying constituents of tissue is the change which occurs in the hydrogen-bound states of water. As the temperature is raised, there is an exchange of water species from the hydrogen-bound to non-hydrogen bonding. The aim of this thesis is to determine tissue temperature from NIR spectral profiles of tissue as temperature is increased. A NIR probe was used to obtain spectral profiles for a series of tissue measurements. / Using the data sets obtained, in-vitro measurements conducted on bovine lung tissues show that temperature can be measured to 1.0°C. Likewise, in-vivo measurements conducted on the human finger also show that temperature can be measured to 2.1°C precision. These measurements suggest that tissue temperature can be measured in living systems using NIR temperature detection.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.30375 |
| Date | January 2000 |
| Creators | Farfara, Ania Maria. |
| Contributors | Burns, David (advisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science (Department of Chemistry.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 001764699, proquestno: MQ64351, Theses scanned by UMI/ProQuest. |
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