A novel reaction for the dehalogenation of aryl halides is discussed in terms of its stoichiometry, mechanism, yields and potential for analytical purposes. The active dehalogenation reagent can be prepared through the reaction of molten potassium with polyethylene glycols (MW $>$ 200), in the absence of oxygen, to form the corresponding potassium glycolate, a powerful nucleophilic agent. This reaction is applied to the determination of PCBs in waste oils. Following dechlorination, the reaction sample is analyzed for chloride using a flow-injection analysis system employing a novel thin-layer amperometric detector with a silver working electrode. / The liquid chromatographic retention behaviour, separation and detection (UV and electrochemical) of nineteen monoaromatic chlorophenols was investigated on a $ beta$-cyclo-dextrin bonded-phase column with respect to mobile phase composition, pH, temperature and ionic strength; this behaviour was compared with other reversed phase columns. The same methodology was also applied to the study of the retention behaviour and gradient elution separation of fourteen diaromatic chlorophenols (PCB metabolic analogues).
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.74598 |
| Date | January 1990 |
| Creators | Paleologou, Michael |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Doctor of Philosophy (Department of Chemistry.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 001238219, proquestno: AAINN67479, Theses scanned by UMI/ProQuest. |
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