The discorhabdins are a family of chemically and biologically interesting natural products. Previous syntheses of these complex substances have all been very similar; this similarity is limiting to the flexibility of these approaches. We describe a general method which we believe can diverge to make any number of the natural products. This route is based on novel benzoquinone photochemistry followed by an annulation onto a quinone monoketal to give the core structure. This core can then be advanced appropriately to form the natural products.*
*Please refer to dissertation for diagrams.
| Identifer | oai:union.ndltd.org:RICE/oai:scholarship.rice.edu:1911/19572 |
| Date | January 2000 |
| Creators | Yates, Matthew H. |
| Contributors | Ciufolini, Marco A. |
| Source Sets | Rice University |
| Language | English |
| Detected Language | English |
| Type | Thesis, Text |
| Format | 196 p., application/pdf |
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